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[JN15214]ZNHIT1抗原(重组蛋白)

价格:0

货号:JN15214

规格: 1mg 100ug

联系方式:021-54479081

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中文名称:   ZNHIT1抗原(重组蛋白)


英文名称: ZNHIT1 Antigen (Recombinant Protein)


别       名: CG1I; ZNFN4A1


储       存: 冷冻(-20℃)


相关类别: 抗原


概述


Full length fusion protein


技术规格


Full name:

zinc finger HIT-type containing 1

Synonyms:

CG1I; ZNFN4A1

Swissprot:

O43257

Gene Accession:

BC017333

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

ZNHIT1 (zinc finger, HIT-type containing 1), also known as CG1I (cyclin-G1-binding protein 1), p18 hamlet or ZNFN4A1 (zinc finger protein subfamily 4A member 1), is a 154 amino acid protein that plays a role in the induction of p53-mediated apoptosis. A member of the ZNHIT1 family, ZNHIT1 contains one HIT-type zinc finger and interacts with p38. ZNHIT1 undergoes post-translational phosphorylation and is encoded by a gene that maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance.

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