兔抗PPOX多克隆抗体

Background:

This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

Applications:

ELISA, IHC

Name of antibody:

PPOX

Immunogen:

Fusion protein of human PPOX

Full name:

protoporphyrinogen oxidase

Synonyms:

VP; PPO; V290M

SwissProt:

P50336

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human esophagus cancer

IHC Recommend dilution:

50-300