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Background:
This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.
Applications:
ELISA, WB, IHC
Name of antibody:
TMPRSS11D
Immunogen:
Fusion protein of human TMPRSS11D
Full name:
transmembrane serine protease 11D
Synonyms:
HAT
SwissProt:
O60235
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human lung cancer and Human liver cancer
IHC Recommend dilution:
100-300
WB Predicted band size:
46 kDa
WB Positive control:
Rat liver tissue lysate
WB Recommended dilution:
1000-5000