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Background:
This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.
Applications:
ELISA, IHC
Name of antibody:
TERF2
Immunogen:
Synthetic peptide of human TERF2
Full name:
telomeric repeat binding factor 2
Synonyms:
TRF2; TRBF2
SwissProt:
Q15554
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human colon cancer
IHC Recommend dilution:
50-200