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技术规格
Background:
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Applications:
ELISA, WB, IHC
Name of antibody:
TMED10
Immunogen:
Fusion protein of human TMED10
Full name:
transmembrane p24 trafficking protein 10
Synonyms:
p23; TMP21; p24d1; S31I125; Tmp-21-I; S31III125; P24(DELTA)
SwissProt:
P49755
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human lung cancer and Human liver cancer
IHC Recommend dilution:
50-200
WB Predicted band size:
25 kDa
WB Positive control:
NIH/3T3 cell, Mouse Pancreas tissue, Rat lung tissue, Mouse liver tissue, Hela, Raji cell lysates
WB Recommended dilution:
1000-5000