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技术规格
Background:
Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe3+ to Fe2+. Can also reduce of Cu2+ to Cu1+, suggesting that it participates in copper homeostasis. Uses NADP+ as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
Applications:
WB, IF
Name of antibody:
STEAP3
Immunogen:
Synthesized peptide derived from internal of human STEA3.
Full name:
STEAP family member 3, metalloreductase
Synonyms:
STMP3; TSAP6; AHMIO2; dudlin-2
SwissProt:
Q658P3
WB Predicted band size:
55 kDa
WB Positive control:
COLO205 cells lysate
WB Recommended dilution:
500-3000
IF positive control:
Hela cells
IF Recommend dilution:
100-500