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Background:
This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants.
Applications:
ELISA, IHC
Name of antibody:
TLK2
Immunogen:
Fusion protein of human TLK2
Full name:
tousled like kinase 2
Synonyms:
HsHPK; MRD57; PKU-ALPHA
SwissProt:
Q86UE8
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human gastric cancer and Human colorectal cancer
IHC Recommend dilution:
50-200