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Background:
Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress (PubMed:21266351). Binds to double-stranded RNA or DNA without sequence specificity (PubMed:25512524). Involved in development of the eye and of primordial germ cells (By similarity).
Applications:
ELISA, WB, IHC
Name of antibody:
PUM3
Immunogen:
Synthetic peptide of human PUM3
Full name:
pumilio RNA binding family member 3
Synonyms:
PEN; HA-8; PUF6; XTP5; PUF-A; HLA-HA8; KIAA0020
SwissProt:
Q15397
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human breast cancer
IHC Recommend dilution:
50-200
WB Predicted band size:
74 kDa
WB Positive control:
Raji cell lysate
WB Recommended dilution:
1000-5000