兔抗PIAS3多克隆抗体

Background:

This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.

Applications:

ELISA, IHC

Name of antibody:

PIAS3

Immunogen:

Synthetic peptide of human PIAS3

Full name:

protein inhibitor of activated STAT 3

Synonyms:

ZMIZ5

SwissProt:

Q9Y6X2

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and human ovarian cancer

IHC Recommend dilution:

25-100