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技术规格
Background:
The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
Applications:
WB
Name of antibody:
RAD18
Immunogen:
Synthesized peptide derived from internal of human RAD18.
Full name:
RAD18 E3 ubiquitin protein ligase
Synonyms:
RNF73
SwissProt:
Q9NS91
WB Predicted band size:
56 kDa
WB Positive control:
LOVO cells, HepG2 cells and K562 cells lysates
WB Recommended dilution:
500-3000