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技术规格
WB Recommended dilution:
100-500
IHC Recommend dilution:
10-50
SwissProt:
P33778
Synonyms:
H2B.1; H2B/f; H2BFF; HIST1H2BB
Full name:
H2B clustered histone 3
Immunogen:
KLH conjugated synthetic peptide derived from human H2BC3
Name of antibody:
H2BC3
Applications:
ELISA, WB, IHC
Back ground:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]