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技术规格
Background:
This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.
Applications:
ELISA, IHC
Name of antibody:
RHEB
Immunogen:
Fusion protein of human RHEB
Full name:
Ras homolog enriched in brain
Synonyms:
RHEB2
SwissProt:
Q15382
ELISA Recommended dilution:
1000-2000
IHC positive control:
Human brain
IHC Recommend dilution:
10-50