兔抗NPY多克隆抗体

Background:

This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi.

Applications:

ELISA, WB

Name of antibody:

NPY

Immunogen:

Fusion protein of human NPY

Full name:

neuropeptide Y

Synonyms:

PYY4

SwissProt:

P01303

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

11 kDa

WB Positive control:

Mouse adrenal gland tissue lysate

WB Recommended dilution:

1000-5000