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Background:
This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function.
Applications:
ELISA, WB, IHC
Name of antibody:
RRBP1
Immunogen:
Fusion protein of human RRBP1
Full name:
ribosome binding protein 1
Synonyms:
RRp; hES; ES130; ES/130
SwissProt:
Q9P2E9
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human breast cancer and human liver cancer
IHC Recommend dilution:
25-100
WB Predicted band size:
152 kDa
WB Positive control:
K562 cells
WB Recommended dilution:
500-2000