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Background:
The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency.
Applications:
IHC, IF
Name of antibody:
SERPIND1
Immunogen:
Synthesized peptide derived from internal of human Heparin Cofactor II.
Full name:
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
Synonyms:
HC2; LS2; HCF2; HCII; HLS2; THPH10; D22S673
SwissProt:
P05546
IHC positive control:
Human liver carcinoma tissue
IHC Recommend dilution:
50-100
IF positive control:
HepG2 cells
IF Recommend dilution:
100-500