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Background:
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
Applications:
ELISA, WB, IHC
Name of antibody:
GSTP1
Immunogen:
Fusion protein of human GSTP1
Full name:
glutathione S-transferase pi 1
Synonyms:
PI; DFN7; GST3; GSTP; FAEES3; HEL-S-22
SwissProt:
P09211
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human liver cancer and human thyroid cancer
IHC Recommend dilution:
100-300
WB Predicted band size:
23 kDa
WB Positive control:
HT-29 cells and human fetal brain tissue
WB Recommended dilution:
500-2000