兔抗PRMT2多克隆抗体

Background:

Protein arginine N-methyltransferase 2 is an enzyme that in humans is encoded by the PRMT2 gene. Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation.

Applications:

ELISA, IHC

Name of antibody:

PRMT2

Immunogen:

Fusion protein of human PRMT2

Full name:

protein arginine methyltransferase 2

Synonyms：

HRMT1L1

SwissProt:

P55345

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human tonsil and human ovarian cancer

IHC Recommend dilution:

25-100