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技术规格
Background:
This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
Applications:
ELISA, WB, IHC
Name of antibody:
RNASE1
Immunogen:
Fusion protein of human RNASE1
Full name:
ribonuclease A family member 1, pancreatic
Synonyms:
RAC1; RIB1; RNS1
SwissProt:
P07998
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human cervical cancer
IHC Recommend dilution:
50-100
WB Predicted band size:
18 kDa
WB Positive control:
Rat pancreas tissue and Mouse pancreas tissue lysates
WB Recommended dilution:
500-2000