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技术规格
Background:
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.
Applications:
WB
Name of antibody:
RPS6KA1 (Phospho-Ser352)
Immunogen:
Synthetic peptide of human RPS6KA1 (Phospho-Ser352)
Full name:
ribosomal protein S6 kinase, 90kDa, polypeptide 1 (Phospho-Ser352)
Synonyms:
RSK; HU-1; RSK1; MAPKAPK1A
SwissProt:
Q15418
WB Predicted band size:
90 kDa
WB Positive control:
HUVEC cells
WB Recommended dilution:
500-1000