兔抗SKP1多克隆抗体

Background:

This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.

Applications:

ELISA, WB, IHC

Name of antibody:

SKP1

Immunogen:

Fusion protein of human SKP1

Full name:

S-phase kinase-associated protein 1

Synonyms：

OCP2, p19A, EMC19, SKP1A, OCP-II, TCEB1L

SwissProt:

P63208

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human breast cancer and Human ovarian cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

19 kDa

WB Positive control:

Mouse brain tissue and NIH/3T3 cells

WB Recommended dilution:

500-2000