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技术规格
Background:
The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.
Applications:
ELISA, IHC
Name of antibody:
SH2B2
Immunogen:
Synthetic peptide of human SH2B2
Full name:
SH2B adaptor protein 2
Synonyms:
APS
SwissProt:
O14492
ELISA Recommended dilution:
1000-2000
IHC positive control:
Human thyroid cancer and Human gastric cancer
IHC Recommend dilution:
15-50