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技术规格
Background:
Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants.
Applications:
ELISA, IHC
Name of antibody:
GYPC
Immunogen:
Fusion protein of human GYPC
Full name:
glycophorin C
Synonyms:
GE; GPC; GPD; GYPD; CD236; PAS-2; CD236R; PAS-2
SwissProt:
P04921
ELISA Recommended dilution:
2000-10000
IHC positive control:
Human colon cancer and Human tonsil
IHC Recommend dilution:
100-300