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技术规格
Background:
The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B).
Applications:
ELISA, IHC
Name of antibody:
RNF7
Immunogen:
Fusion protein of human RNF7
Full name:
ring finger protein 7
Synonyms:
SAG; ROC2; CKBBP1
SwissProt:
Q9UBF6
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human liver cancer and human tonsil
IHC Recommend dilution:
20-100