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Background: |
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. |
Applications: |
WB |
Name of antibody: |
RPS6KB2(Ab-423) |
Immunogen: |
Synthesized non-phosphopeptide derived from human p70 S6 Kinase β around the phosphorylation site of serine 423 (P-V-S(p)-P-L). |
Full name: |
ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
Synonyms: |
KLS; SRK; S6K2; STK14B; p70S6Kb; P70-beta; S6K-beta2; P70-beta-1; P70-beta-2; p70(S6K)-beta |
SwissProt: |
Q9UBS0 |
WB Predicted band size: |
53 kDa |
WB Positive control: |
293 cells lysate |
WB Recommended dilution: |
500-3000 |