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技术规格
Background:
Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like.
Applications:
ELISA, WB, IHC
Name of antibody:
SIGLEC12
Immunogen:
Fusion protein of human SIGLEC12
Full name:
sialic acid binding Ig-like lectin 12 (gene/pseudogene)
Synonyms:
S2V; SLG; SIGLECL1; Siglec-XII
SwissProt:
Q96PQ1
ELISA Recommended dilution:
1000-2000
IHC positive control:
Human prostate cancer
IHC Recommend dilution:
25-100
WB Predicted band size:
65 kDa
WB Positive control:
Mouse bladder tissue
WB Recommended dilution:
200-1000