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技术规格
Background:
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
Applications:
ELISA, WB, IHC
Name of antibody:
PVR
Immunogen:
Fusion protein of human PVR
Full name:
poliovirus receptor
Synonyms:
PVS; HVED; CD155; NECL5; TAGE4; Necl-5
SwissProt:
P15151
ELISA Recommended dilution:
1000-2000
IHC positive control:
Human liver cancer and Human colon cancer
IHC Recommend dilution:
25-100
WB Predicted band size:
45 kDa
WB Positive control:
HepG2 cells, human testis tissue and Hela cells
WB Recommended dilution:
200-1000