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兔抗MAP2K3多克隆抗体

品牌:纪宁生物

货号:JN1843

规格: 100ul 200ul 25ul

联系方式:021-66980655

立即询价 说明书下载

产品详情

中文名称:  兔抗MAP2K3多克隆抗体


英文名称:  Anti-MAP2K3 rabbit polyclonal antibody


别      名:  MEK3; MKK3; MAPKK3; PRKMK3; SAPKK2; SAPKK-2


抗     原:  MAP2K3

 

相关类别:  一抗

储     存:  冷冻(-20℃)


宿     主:  Rabbit


反应种属:  Human, Mouse


标  记  物:  Unconjugate


克隆类型:  rabbit polyclonal


技术规格


Background:

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene.

Applications:

ELISA, IHC

Name of antibody:

MAP2K3

Immunogen:

Fusion protein of human MAP2K3

Full name:

mitogen-activated protein kinase kinase 3

Synonyms:

MEK3; MKK3; MAPKK3; PRKMK3; SAPKK2; SAPKK-2

SwissProt:

P46734

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human ovarian cancer and human gastric cancer

IHC Recommend dilution:

25-100







友情链接:
elisa试剂盒 elisa检测试剂盒 elisakit 植物elisa试剂盒 CAS号数据库
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