兔抗PA2G4多克隆抗体

Background:

This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified.

Applications:

ELISA, IHC

Name of antibody:

PA2G4

Immunogen:

Fusion protein of human PA2G4

Full name:

proliferation-associated 2G4

Synonyms:

EBP1; HG4-1; p38-2G4

SwissProt:

Q9UQ80

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human brain

IHC Recommend dilution:

50-200