手机扫码访问本站
微信咨询
英文名称： ZKSCAN3 Antigen (Recombinant Protein)
别 名： zinc finger with KRAB and SCAN domains 3; ZF47; Zfp47; ZFP306; ZNF306; ZNF309; zfp-47; ZSCAN13; ZSCAN35; dJ874C20.1;
dJ874C20.1.
相关类别： 抗原
储 存： 冷冻（-20℃）
概述
|
Fusion protein corresponding to a region derived from 339-538 amino acids of human ZKSCAN3 |
|
Full name: |
zinc finger with KRAB and SCAN domains 3 |
|
Synonyms: |
ZF47; Zfp47; ZFP306; ZNF306; ZNF309; zfp-47; ZSCAN13; ZSCAN35; dJ874C20.1; dJ874C20.1. |
|
Swissprot: |
Q9BRR0 |
|
Gene Accession: |
BC006118 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas. |
