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英文名称： RNF40 Antigen (Recombinant Protein)
别 名： ring finger protein 40, E3 ubiquitin protein ligase; BRE1B; RBP95; STARING
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to C terminal 250 amino acids of human RNF40 |
|
Full name: |
ring finger protein 40, E3 ubiquitin protein ligase |
|
Synonyms: |
BRE1B; RBP95; STARING |
|
Swissprot: |
O75150 |
|
Gene Accession: |
BC006133 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. |
