手机扫码访问本站
微信咨询
英文名称： SETDB1 Antigen (Recombinant Protein)
别 名：ESET; KG1T; KMT1E; TDRD21; H3-K9-HMTase4
储 存： 冷冻（-20℃）
相关类别： 抗原
概述：
|
Fusion protein corresponding to a region derived from 1-200 amino acids of human SETDB1 |
|
Full name: |
SET domain bifurcated 1 |
|
Synonyms: |
ESET; KG1T; KMT1E; TDRD21; H3-K9-HMTase4 |
|
Swissprot: |
Q15047 |
|
Gene Accession: |
BC009362 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described. |
