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英文名称: CDH23 Antigen (Recombinant Protein)
别 名: USH1D, CDHR23
储 存: 冷冻(-20℃)
相关类别: 抗原
概述
Fusion protein corresponding to C terminal 250 amino acids of human CDH23 |
技术规格
Full name: |
cadherin-related 23 |
Synonyms: |
USH1D, CDHR23 |
Swissprot: |
Q9H251 |
Gene Accession: |
BC139903 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described. |