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英文名称: CDA Antigen (Recombinant Protein)
别 名: CDD
储 存: 冷冻(-20℃)
相关类别: 抗原
概述
Full length fusion protein |
技术规格
Full name: |
cytidine deaminase |
Synonyms: |
CDD |
Swissprot: |
P32320 |
Gene Accession: |
BC054036 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias. |