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英文名称: C1GALT1C1 Antigen (Recombinant Protein)
别 名: C1GALT1 specific chaperone 1; TNPS; COSMC; MST143; C1GALT2; HSPC067; C38H2-L1
相关类别: 抗原
储 存: 冷冻(-20℃)
概述
Fusion protein corresponding to a region derived from 119-318 amino acids of human C1GALT1C1 |
技术规格
Full name: |
C1GALT1 specific chaperone 1 |
Synonyms: |
TNPS; COSMC; MST143; C1GALT2; HSPC067; C38H2-L1 |
Swissprot: |
Q96EU7 |
Gene Accession: |
BC011930 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. |