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Background: |
The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
XPNPEP3 |
Immunogen: |
Fusion protein of human XPNPEP3 |
Full name: |
X-prolyl aminopeptidase 3 |
Synonyms: |
APP3; ICP55; NPHPL1 |
SwissProt: |
Q9NQH7 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human ovarian cancer and Human tonsil |
IHC Recommend dilution: |
30-150 |
WB Predicted band size: |
57 kDa |
WB Positive control: |
PC-3 and 293T cell lysates |
WB Recommended dilution: |
200-1000 |