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英文名称: SRC Antigen (Recombinant Protein)
别 名: ASV; SRC1; c-SRC; p60-Src
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述
Fusion protein corresponding to a region derived from 270-523 amino acids of human SRC |
技术规格
Full name: |
SRC proto-oncogene, non-receptor tyrosine kinase |
Synonyms: |
ASV; SRC1; c-SRC; p60-Src |
Swissprot: |
P12931 |
Gene Accession: |
BC011566 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. |