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英文名称: SIRT3 Antigen (Recombinant Protein)
别 名: SIR2L3
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述
Fusion protein corresponding to a region derived from 126-382 amino acids of human SIRT3 |
技术规格
Full name: |
Sirtuin 3 |
Synonyms: |
SIR2L3 |
Swissprot: |
Q9NTG7 |
Gene Accession: |
BC001042 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. |