兔抗VIM多克隆抗体

Background:

This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients.

Applications:

ELISA, WB, IHC

Name of antibody:

VIM

Immunogen:

Fusion protein of human VIM

Full name:

vimentin

SwissProt:

P08670

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human liver cancer

IHC Recommend dilution:

50-300

WB Predicted band size:

54 kDa

WB Positive control:

Hela cell lysate

WB Recommended dilution:

2000-5000