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英文名称： RCHY1 Antigen (Recombinant Protein)
别 名： ZCHY; ARNIP; CHIMP; PIRH2; RNF199; ZNF363; PRO1996
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to a region derived from 1-261 amino acids of human RCHY1 |
技术规格
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Full name: |
ring finger and CHY zinc finger domain containing 1 |
|
Synonyms: |
ZCHY; ARNIP; CHIMP; PIRH2; RNF199; ZNF363; PRO1996 |
|
Swissprot: |
Q96PM5 |
|
Gene Accession: |
BC047393 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
