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Fusion protein corresponding to a region derived from 200-419 amino acids of human RARA |
技术规格
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Full name: |
Retinoic acid receptor, alpha |
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Synonyms: |
RAR; NR1B1 |
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Swissprot: |
P10276 |
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Gene Accession: |
BC008727 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus. |
