兔抗VAV3多克隆抗体

Background:

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Applications:

ELISA, IHC

Name of antibody:

VAV3

Immunogen:

Synthetic peptide of human VAV3

Full name:

vav guanine nucleotide exchange factor 3

SwissProt:

Q9UKW4

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and human tonsil

IHC Recommend dilution:

25-100