兔抗VAV3(Phospho-Tyr173) 多克隆抗体

Background:

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Applications:

WB

Name of antibody:

VAV3(Phospho-Tyr173)

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 173 (E-V-Y(p)-E-D) derived from Human VAV3.

Full name:

vav 3 guanine nucleotide exchange factor

Synonyms：

0

SwissProt:

Q9UKW4

WB Predicted band size:

98 kDa

WB Positive control:

Jurkat cells lysates

WB Recommended dilution:

500-1000