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PRCP抗原(重组蛋白)

品牌:纪宁生物

货号:JN15256

规格: 1mg 100ug

联系方式:021-66980655

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产品详情

中文名称:  PRCP抗原(重组蛋白)


英文名称 PRCP Antigen (Recombinant Protein)


别      名: PCP; HUMPCP


储      存: 冷冻(-20℃)


相关类别: 抗原


概 述


Fusion protein corresponding to a region derived from 46-317 amino acids of human PRCP


技术规格


Full name:

Prolylcarboxypeptidase (angiotensinase C)

Synonyms:

PCP; HUMPCP

Swissprot:

P42785

Gene Accession:

BC001500

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

 

友情链接:
elisa试剂盒 elisa检测试剂盒 elisakit 植物elisa试剂盒 CAS号数据库
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