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技术规格
Background: |
Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]). |
Applications: |
ELISA, IHC |
Name of antibody: |
USP5 |
Immunogen: |
Fusion protein of human USP5 |
Full name: |
ubiquitin specific peptidase 5 (isopeptidase T) |
Synonyms: |
ISOT |
SwissProt: |
P45974 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human thyroid cancer and Human esophagus cancer |
IHC Recommend dilution: |
25-100 |