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Background: |
Acts as a novel regulator of senescence. Involved in the formation of senescence-associated heterochromatin foci (SAHF), which represses expression of proliferation-promoting genes. Binds to proliferation-promoting genes. May be required for replication-independent chromatin assembly. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
UBN1 |
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Immunogen: |
Synthetic peptide of human UBN1 |
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Full name: |
ubinuclein 1 |
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Synonyms: |
VT; VT4 |
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SwissProt: |
Q9NPG3 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human ovarian cancer and human tonsil |
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IHC Recommend dilution: |
50-300 |
