兔抗UBE2R2多克隆抗体

Background:

Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.

Applications:

ELISA, IHC

Name of antibody:

UBE2R2

Immunogen:

Fusion protein of human UBE2R2

Full name:

ubiquitin conjugating enzyme E2 R2

Synonyms:

UBC3B; CDC34B; E2-CDC34B

SwissProt:

Q712K3

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer and Human tonsil

IHC Recommend dilution:

150-300