兔抗UBE2A多克隆抗体

Background:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

UBE2A

Immunogen:

Fusion protein of human UBE2A

Full name:

ubiquitin conjugating enzyme E2 A

Synonyms:

UBC2; HHR6A; MRXSN; RAD6A; MRXS30

SwissProt:

P49459

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human cervical cancer and Human colorectal cancer

IHC Recommend dilution:

50-300