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Background: |
Participates both in methylation of protein and tRNA species. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
TRMT112 |
Immunogen: |
Synthetic peptide of human TRMT112 |
Full name: |
tRNA methyltransferase subunit 11-2 |
Synonyms: |
TRM112; HSPC152; HSPC170; hTrm112; TRMT11-2 |
SwissProt: |
Q9UI30 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human ovarian cancer and Human lung cancer |
IHC Recommend dilution: |
40-200 |
WB Predicted band size: |
14 kDa |
WB Positive control: |
231, A172, A549, HepG2, PC3 and Hela cell lysates |
WB Recommended dilution: |
200-1000 |