兔抗GJA1(Phospho-Ser265) 多克隆抗体

Background:

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014]

Applications:

WB

Name of antibody:

GJA1(Phospho-Ser265)

Immunogen:

Peptide sequence around phosphorylation site of Serine 265(Q-K-Y(p)-A-Y) derived from Human Connexin 43.

Full name:

gap junction protein, alpha 1, 43kDa

Synonyms：

HSS; CMDR; CX43; GJAL; ODDD; AVSD3; HLHS1

SwissProt:

P17302

WB Predicted band size:

43 kDa

WB Positive control:

Huvec cells lysates

WB Recommended dilution:

500-1000