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Background: |
GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide. |
Applications: |
IHC |
Name of antibody: |
GCHFR |
Immunogen: |
Synthesized peptide derived from internal of human GCHFR. |
Full name: |
GTP cyclohydrolase I feedback regulator |
Synonyms: |
P35; GFRP; HsT16933 |
SwissProt: |
P30047 |
IHC positive control: |
Human colon carcinoma tissue |
IHC Recommend dilution: |
50-100 |